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6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile

Product Name
6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
CAS No.
1207836-10-9
Chemical Name
6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
Synonyms
LOXO-292 intermediate;6-Bromo-4-methoxypyrazoL;Selpercatinib intermediate;o[1,5-a]pyridine-3-carbonitriL;6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonit;6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-bromo-4-methoxypyrazolol[.5-alpyridine-3-carbonitrile;6-bromo-4-methoxypyrazole[1,5-a]pyridine-3-carbonitrile;6-Bromo-4-methoxypyrazolo [1,5-A] pyridine-3-acetonitrile;Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-bromo-4-methoxy-
CBNumber
CB83143962
Molecular Formula
C9H6BrN3O
Formula Weight
252.07
MOL File
1207836-10-9.mol
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6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile Property

Density 
1.67±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
-1.97±0.30(Predicted)
InChI
InChI=1S/C9H6BrN3O/c1-14-8-2-7(10)5-13-9(8)6(3-11)4-12-13/h2,4-5H,1H3
InChIKey
JTEWRYBKHXGXHP-UHFFFAOYSA-N
SMILES
C12=C(C#N)C=NN1C=C(Br)C=C2OC
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific
Product number
0400DP
Product name
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
Packaging
5g
Price
$1275
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0621203
Product name
6-BROMO-4-METHOXYPYRAZOLO[1,5-A]PYRIDINE-3-CARBONITRILE
Purity
95.00%
Packaging
5MG
Price
$502.68
Updated
2021/12/16
Ambeed
Product number
A866632
Product name
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
Purity
95%
Packaging
100g
Price
$920
Updated
2021/12/16
Chemenu
Product number
CM325273
Product name
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
Purity
95+%
Packaging
100g
Price
$1263
Updated
2021/12/16
Crysdot
Product number
CD11373512
Product name
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
Purity
98%
Packaging
5g
Price
$1663
Updated
2021/12/16
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6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile Chemical Properties,Usage,Production

Uses

6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile is an organic intermediate for laboratory R&D processes.

Synthesis

The DMF 10L solution of 2,4,6-trimethylbenzenesulfonic acid 3-bromo-5-methoxypyridinamine salt 2000g (4.96mol, 1.0eq), 2-chloropropene cyanide (7.44mol, 1.5eq) was added with potassium carbonate 684g (4.96mol, 1.0eq) and stirred at 20-30°C for 8h. Then the mixtrue was heated with dropwise 1132g (7.44mol, 1.5eq) of diazabicyclo at 50-60°C for 20h. After the reaction is finished and poured into water 30 L at RT. the solution was filtered, washed with water and recrystallized in ethanol to give a pale yellow solid, 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile (702g 56%).

6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile Suppliers

China 131 India 1 United States 3 Global 135
Accela ChemBio Inc.
Tel
(+1)-858-699-3322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
19965
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52927
Advantage
58
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View Lastest Price from 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
Selpercatinib intermediate 1207836-10-9
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-05-16
hebei hongtan Biotechnology Co., Ltd
Product
6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile 1207836-10-9
Price
US $75.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000kg
Release date
2024-05-17
Jinan Million Pharmaceutical Co., Ltd
Product
6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile 1207836-10-9
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1200KG/M
Release date
2023-08-11

1207836-10-9, 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrileRelated Search:


  • 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
  • 6-Bromo-4-methoxypyrazoL
  • o[1,5-a]pyridine-3-carbonitriL
  • Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-bromo-4-methoxy-
  • LOXO-292 intermediate
  • 6-bromo-4-methoxypyrazole[1,5-a]pyridine-3-carbonitrile
  • 6-bromo-4-methoxypyrazolol[.5-alpyridine-3-carbonitrile
  • 6-Bromo-4-methoxypyrazolo [1,5-A] pyridine-3-acetonitrile
  • 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonit
  • Selpercatinib intermediate
  • 1207836-10-9
  • 1207863-10-9
  • 1207836-10-9